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Why medication sometimes doesn't help, why a B-complex can worsen depression, why postpartum depression is often linked to copper overload, or why your results are "within normal range" yet you still don't feel well — the answers are grounded in the orthomolecular approach and published research.
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Copper overload
In copper overload, free copper in serum is higher than ceruloplasmin can bind. The result is a nervous system that overreacts to everything — from stress to sleep to hormones. Here are all the mechanisms and the exact steps to check for it.
Read articlePyroluria — anxiety and sleep
In pyroluria the body loses zinc and vitamin B6 through urine — the two most important nutrients for producing serotonin, GABA, and melatonin. The result: anxiety that does not respond to medication, and sleep that cannot be "caught up on". Here is the full mechanism.
Read articleZinc — the most underrated mineral
Zinc is a cofactor for more than 300 enzymes and is key to neurotransmitter production, immunity, skin, hormones, and copper regulation. Its deficiency hides behind symptoms rarely linked to zinc. Here is the full picture — including the plasma test and how to safely replenish zinc.
Read articleSSRIs explained
SSRIs block serotonin reuptake, but that doesn't explain why, with the exact same diagnosis, they work beautifully for one person and not at all for another — or why they sometimes stop working after a while. An orthomolecular look at what is happening underneath.
Read articleSNRIs explained
SNRIs block the reuptake of both serotonin and norepinephrine at once. We explain when this "dual" mechanism makes sense, why it can worsen copper overload — and how to tell the difference.
Read articleADHD medications explained
The same stimulant improves focus in one child and leaves another irritable and unable to sleep. We explain how ADHD medications work, what affects tolerability — and what the Walsh view says about pyroluria, copper, and zinc.
Read articleMood stabilizers
Mood stabilizers prevent mania, hypomania, and bipolar depression, but none of them treats every phase equally well. We explain the differences between medications — and what the Walsh view says about sleep, copper, zinc, and methylation as triggers for mood swings.
Read articleAntipsychotics explained
Antipsychotics act on dopamine receptors, and during acute psychosis or mania they can be lifesaving for functioning and safety. With long-term use, though, they require active monitoring of metabolism, movement, and hormones. We explain the mechanism and what to watch.
Read articleMedications and biochemistry
A "depression" diagnosis alone doesn't say which medication will work. An overview of the five biochemical patterns per the orthomolecular approach, and why the same medication helps one person and burdens another.
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