Histamine Test (whole blood) — €149
Recommended first test for this path.
See the test Order directly →Biotype 3 — Histapenia
Histapenia (overmethylation, low histamine)
High anxiety, panic, possibly paranoid thoughts. You've tried SSRIs and they made things worse. Sensitivity to chemicals and supplements. Dry eyes, dry mouth. No seasonal allergies.
Read more: Histamine and Mental Health — the Neurotransmitter People Forget About
Is this me?
When this path makes sense
Histapenia ("overmethylation" in the English-language literature) is the opposite of histadelia — an excess of methyl groups in the CNS and low blood histamine. Activity of the SERT and DAT transporters is reduced, so synaptic serotonin and dopamine run high — paradoxically producing anxious and paranoid symptoms. Walsh's data shows histapenics make up roughly 18% of the general population, and most respond poorly to SSRIs and methionine. Nutrients associated with support in this profile: folate (5-MTHF), B12, niacin — a specialist decides on suitability and dosing after testing. Copper overload is a frequent co-occurring finding. Clinically: high anxiety, panic, paranoid thinking, hyperactivity, dry eyes and mouth, absence of seasonal allergies, history of eczema, improvement on lithium or benzodiazepines, worsening on SSRIs and methionine.
Panic attacks
Insomnia
Chemical sensitivity
Emotional instability
Paranoia
High anxiety
Dry eyes/mouth
Hyperactivity
Next step
Start with a test, not guesswork.
This path isn't about buying five supplements right away. First confirm the area that best matches your symptoms. Only then does it make sense to act on the result with supplements or a consultation.
After the result
What's worth addressing next
The test is only the start — the real value comes once you pair the result with a consultation and targeted nutritional support for your biotype. Here are the usual next steps.
Path
Practical plan
- Fill in the orientational screening — it checks whether your symptoms are compatible with this biotype.
- Order the Histamine Test (€149) — the sample is collected at home or at a local laboratory.
- Once the result is in, targeted nutritional support (Histamin Plus) is handled in the Consultation with a Doctor / Therapist (€149).